In the (grand) scheme of things phrase
"Grand" can be replaced by "great" or "whole"
Taking everything in account
In the great scheme of things, the journey was great.
There are some minor flaws, but they won't affect your score in the grand scheme of things.
The origin of this phrase is not clear.
hurt someone or yourself
If you try to carry that suitcase, you’ll do yourself a mischief.