Lose (one's) buttons verb phrase
To be mentally deficient or incompetent; to become of mental health disorders
My wife started losing her buttons after menopause.
I have stayed up all night to accomplish the report, so I am losing my buttons.
If someone is not right in the head, he or she doesn't have a normal mental state or condition.
To become stupid, foolish, silly or crazy
To lose mental control; to become very anxious, upset, or afraid
Unstable, mentally unbalanced state.
To be unintelligent or mentally deranged.
The verb "lose" should be conjugated according to its tense.
To punish someone or something harshly
He's a really strict teacher, so he'll definitely lower the boom on you if you don't do your homework.