Set off (for some place) verb phrase
To leave a place, especially to start a journey
We're going to set off early tomorrow.
I'm planning to set off for China this July.
To leave at a favorable moment
Travel extensively and acquire a diverse range of experiences
1. To move or depart from some place in a very quick or hurried manner
2. To leave something or some place very lazily or reluctantly
To depart quickly and suddenly
I have to leave now.
If you fall for someone's trick the first time then they are at fault.
Are you going to mess with me again? Fool me once, shame on you; fool me twice, shame on me.