That's the rub phrase
That is the biggest or most difficult problem (with the situation being discussed)
A: "Why don't you buy something to eat, man?" B: "That's the rub! I don't have any money left."
A: "You really should get your life together!" B: "That's the rub, man! I don't know what to do right now."
A problem or difficult circumstance
To have to accept some troubles or worries that must be handled by oneself
Completely controlling over a scenario or situation.
This is a line from Shakespeare's Hamlet:
"To die — to sleep.
To sleep — perchance to dream: ay, there’s the rub!
For in that sleep of death what dreams may come
When we have shuffled off this mortal coil,
Must give us pause."
To decide to believe someone‘s saying although they may not tell the truth
He said that he was late because he had an accident and I gave him the benefit of the doubt.