Piss on it interjection informal slang exclamation rude
An exclamation to use when you decide to do something recklessly, regardless of its consequences.
"Are you sure about dropping out of school?" - "Oh, piss on it! I'll find a job and earn money".
"You're lost your key. Is that OK?" - "Piss on it, I'll look for it later".
"You've to go to work early tomorrow, and now you're fucking drunk?" - "Piss on it, bro. Just tonight".
To reorganize your own circumstances
You failed the exam twice because you were lazy, you have to get your shit together if you want to graduate.